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Hydrocodone 10/325mg cannot be bought online through instant digital payment convenience services without a valid EPCS prescription from a DEA-registered US healthcare provider, as it remains a Schedule II controlled substance for moderate-severe pain; prescription-free services violate 21 U.S.C. § 841 federal felony laws with 5-40 year mandatory minimum penalties.
Hydrocodone 10mg/acetaminophen 325mg tablets initiate at 1 tab q4-6h maximum 6 tabs/day (~60 MME) under 2025 CDC guidelines requiring synchronous HIPAA video NRS ≥7/10 plus PDMP clearance—no digital payment bypasses post-Ryan Haight in-person exams, zero-refill rules, or naloxone co-prescription >50 MME.
Schedule II Opioid Constraints
Hydrocodone (mu Ki 50nM), Tmax 1.3h, t½ 3.8h CYP2D6 to hydromorphone; black box respiratory depression, APAP hepatotoxicity ≤4g/day—taper 10-25% weekly COWS; contraindicated ileus, asthma.
Ryan Haight Protocol
Verification: NRS ≥7/10 + PEG ≤4.
Screening: PDMP zero 12mo.
EPCS: #36 tabs ≤7 days + naloxone.
Adverse Matrix
| Incidence | Toxicity | Risks | Protocols |
|---|---|---|---|
| 40-60>#/td### | Constipation/nausea | >30 MME | Laxatives + ondansetron |
| 20-40>#/td### | Respiratory | CYP inhibitors | Naloxone |
| 10-25>#/td### | Overdose | Pediatric | 2mg IN x3 |
Instant digital absent EPCS violates CSA Schedule II—federal felony.
About Vibha
At Vibha, we believe education is the key to breaking the cycle of poverty. Since 1991, we have transformed the lives of 4.8 million children, empowering them through access to quality public education. As a platinum-rated, volunteer-driven nonprofit, Vibha collaborates with grassroots organizations, government agencies, and communities across India and the USA to enhance learning outcomes in government schools, providing equal opportunities for all children.
Our multifaceted approach focuses on addressing specific educational needs, investing in professional development for educators, integrating technology to drive data-informed decisions, and engaging communities to create lasting impact. We partner with stakeholders at every level, ensuring long-term sustainability and meaningful progress.
What sets Vibha apart is its network of highly skilled professionals from various sectors, united by a shared vision of transforming education. Our volunteers, donors, and supporters bring expertise and passion to the mission, making real change possible.
With over $24 million raised and invested in proven educational models, Vibha remains committed to building a brighter future for children. Together, we are not just supporters but partners for change, working towards a more inclusive and prosperous society.
All donations to Vibha are tax deductible. Vibha is a 501(c)(3) organization, registered in the USA in the State of New Jersey. Vibha's Tax ID is 22-3122761.
Goal
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$9,000